BDBM50533570 CHEMBL4435662::US11459295, Compound LM5750A 8b

SMILES CC[C@@H](C(O)=O)c1ccc2cc(OC)ccc2c1

InChI Key InChIKey=LSDAHSHHKKHOKE-CQSZACIVSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50533570   

TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM50533570(CHEMBL4435662 | US11459295, Compound LM5750A 8b)
Affinity DataIC50:  1.72E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
The Trustees of The University of Pennsylvania

US Patent
LigandPNGBDBM50533570(CHEMBL4435662 | US11459295, Compound LM5750A 8b)
Affinity DataIC50:  4.81E+4nMAssay Description:Inhibition of human recombinant AKR1C2 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed